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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3994a0bb702124bc89c4911a0c8bb0c1fc8634b19ed6be00772be5d2bbf7b55b' 
  AND token = 'CE91S6U0SWQa44cwIme+TR8QAedn9vsUVb/Ax7M0RaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}