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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '83aa70fd8925d59d370778470106a60fbb83db4ec3ca4059bc8e8ccf661fdab6' 
  AND token = 'Ck1++uUzQ/f96g5a8D4af06nPvZmj9rW6Sjs0e5hR4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}