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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ec2b01d271351f06a61f03f572187c574a7f74e845ed071e072305b5451eb9c' 
  AND token = 'nJW3UtKP+3tYX7EBpP2uOyKrHeRsJBp9uH0IrqLX8U8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}