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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '581cbb2ae0f09393121be3df8b7d68549e763dc09e1ea5ec9186ea6e782ac3e8' 
  AND token = 'tJVa+Mv7OI3+NWgDA1YgdS3W2WxSJqDB3vvQm96yQps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}