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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ad9aac0a880679790aa1577b88cc13ecf62a00a7c17b81a555e6428cf68b498' 
  AND token = 'vmZGxNqFDhQIZKYlY1dMTz5xnvDcE0ceTZx5pfr/jQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}