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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b29bd71f257352e3337f459d461023ca4bb9714e67f04c52cf4d017cff5e6996' 
  AND token = '9f1rfsQAq+hV22lSfV3tgVryIQtWrbAOpPl++I6Imi4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}