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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68bacd9fe729a0b0494adb29d07bf39b84ccfcc48960cc4b0cb4fddd29042f11' 
  AND token = 'O3P8tdnXdVbpiGBUoDbaC3Tx4+/C8wKO6F6bwK9YOeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}