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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60e64570c1090d2c5a291b59c080cfea0dc7bd927ab9a6b9d52163c6f89e1ea7' 
  AND token = 'jAGfDEKnTepNNiFSZNEfKYUSr5ez+YfM5QRCpqIynic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}