SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1900b2251bc6ececf823ea72bfe48e58c78f144617a29b41be93f8deddcf2cde' 
  AND token = 'DsOvDYz3+xVioxVhjYoyYZFQRVWv70DogGoHcrak9Hw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}