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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c46263fd3c63b953b4762f51e802611c34fb54e4e52a5de2d97a3e14f279e23' 
  AND token = 'morqIIlPYHQnA7nSdZceoRrArWyj4TROsymXb3Ag5hI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}