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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4ca216a79cb153b28a1a55022c7154e4efdaf61965e10d91feb8930fb0f49c0' 
  AND token = 'ApJzqX+U90r+7I9ggQQpzz10DMg0T48rY97xr0Bu7Ko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}