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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e90e503af8ba75ed7531a602b1a7a47086e82f120f0e7f296c6c74a4f9924b6' 
  AND token = 'JM/XniP8VwaW1UjcoLJS0T/XzjU7ZDtWbZWEBpBdcS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}