SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c22df3ac597a59c18d41e6cc0600f79d02b0e8a419dd4ccfc291efedbc38939' 
  AND token = 'P7Q5tgX5mD4OT6ZtyZg4deX4rRm1v2c/5abOicBQhBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}