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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39a577846489c403748b21f942c25010aed0085e3976f12d5cb7a062ac5f004d' 
  AND token = 'u1LTBL1Y1qf7ScRGkuDDKISanhr1Wc6pWGBGVX3jbnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}