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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6e5ea8c929053656536179fa5dbbf8454d2d9694fbd6a1043168b4616caabe4' 
  AND token = 'swLu46Rk1UwB+xd7Q9jyAXrdH9pIR2dcY7e/3lRAxIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}