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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41ce77e539ef299e96478fa256c41f4702c1bf04d7345234fc09e6035e71c68f' 
  AND token = 'InFNfyXIJi9GAPkhetRFoCHEPY+tuLbuHfh3AI3/M+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}