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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21d708704d1b4479e535977c47e39b9edf136920996757c054861da8970903db' 
  AND token = 'UoGItbFc5HDq8/syXlCEqV/mYUQWi+TMLrul0F53634=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}