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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06be7d10fd4c052da1effde26eef99a57c08a2e4c59e3c5918bc4eb710d88e45' 
  AND token = 'Po9s8Xt0lGjQzd1AC+Jhm+WhOPJxBH/HbuassXya1GM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}