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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b48b7ed87b95cee5e9bab1a9eb5439e8ba5641ca8746e3fbba01e61634d3eda' 
  AND token = 'TB1XwCeM3RuD7kPkiDcbSeGy0ij+IzzlbF/ns5y2ElM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}