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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '246c81adfecaedf669e11a6835ce77ce3bd6bd9563330dd03b6a718af376050e' 
  AND token = '2pjlXKVCojXtaDtrcYisFfUS0kW72veOcXctSfmyn6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}