SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac4c3392eb7f9fd3c7b8c3acf3027f0688998155203cc7d9965048c6ee172131' 
  AND token = 'GhIHDpfvNWCxZXo2vIJVpi3EReUKTRbCM6BKDDQLUKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}