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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be24c67d1663ce5e7e7cbc39d058ce261ff93291df2da55ce2eeb8e94ce87c44' 
  AND token = 'AtH1rMe6v8wNJP4JWVjs2+1zF9aH8bsAvcdNw/d3/aQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}