SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec737a9c09d83c345babf568d0ea63e266f6685ce99b41c6c8a53ef9924502c4' 
  AND token = 'HX/uY7H0HRoT1TozVVjhyUSnJwEfnFpf1sQ3TXxiz/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}