SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9a25d7df4334b07599a0d96f2750af84a479acdc7ee6afa625b7040f51b8af1' 
  AND token = 'gFj0yCLExd9OikZWh8t/8nmzbea46RGAQfm5K6xaSmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}