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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec4e2dc422800a2c036a59bae266f22848b5e8e1bdaf04e3cd6510daca2fb781' 
  AND token = '6jpkEGFXuoSPZwF1MTy07ku+yQJfDU2GOI0iQHUMsu4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}