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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c8946bacf8c46babcd21b2a51ac802cb2c2b7605e1ff95dda0cd7b9b8d246aa' 
  AND token = '4uUtTD6J2RjoaoAjfOL/Ja7DzZDibrGmnBByL+IJxoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}