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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46b0f8cfcca889f22dd9271f27aa884034c3f69ee95f7eeb0f412454a2bd64a8' 
  AND token = 'tCXPJ+j3Tk46TlxA69Ln/TxUEteUUUqowhpRH6oZcuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}