SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '96313cc6190b96502d7faf3a896c869b60333fb20b76c0e4a87b96704754a0c5' 
  AND token = '6fgYGrDDav/EXk0e+YE65FILyX+tZfvE6hfr5HG9YFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}