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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7a690d88504a311ca1840a99d38fec10f2a438eb57f6648e189781a274eda27' 
  AND token = 'IvU1cAwy8yaExoqNp3lczk1bDVlBw0tLeQ/Qal1eE9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}