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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '643fdbd4aa51833e43e2b9da233822e5738290317c0e1de75d527f73091b3d9a' 
  AND token = 'm/atug8T7d00jlg7/DVWcegvXBqsNYcGDQHh+8iNdVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}