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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac3d1e99b313a0aa674064a08d0261f4d8127493f41c2b769853eb8a370fe17c' 
  AND token = 'Y+eOypAML8CW92WunGvZOxn1vPq5WNg5nj7zL6TCMLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}