SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1cadc81a49264e1d4794dbdc7135bb133f20affe27373cf84445cb2f75b8ca5' 
  AND token = 'ilu1r3FMy3lFTn5f+6Cf5waFy45aZeMgCMLYU7srC84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}