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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afd58beee00e6bf864e5274c354271a33119f1ea2af86c8891e2a6f74358c958' 
  AND token = 'uQz6koV57iH4hM7z+XU0xT1rhn+V4nu4wrcJeBTeMAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}