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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47c2b03abd484e95dbf2a79648a8b9f088543f1136544caf24f02530cdc031d4' 
  AND token = 'UY49Cb1aQFB4hj0+iHVYOmEZ2hZs9oJ0BFkiLkspqXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}