SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '380f2eef2d740df0f13def389f3dd2bdd31cceceaffc2335f464ee91e853718e' 
  AND token = 'kwcik9It4Re+y0SdvuovpKDyfVXXgUB6D6FAd6S5BVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}