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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c7ac181692957a26e3d352f8565ac665882f70eb1e90329c87bc699e2b016de' 
  AND token = 'tysSH4VsUnR7MyRypgdkqp9WmBZfZO/ZYdjV1f3OIzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}