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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a2a7b02c2fd974b566db5f88cadf4878967359c13306f8e14f712b1a6721474' 
  AND token = 'iLdjNYrkwYHokgpiESIwIRcHD6+MKEaqCMdLo8IBFpQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}