SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b250568be77b6a84051b16cfd312b143df474c22c80191bf4c73723f85d08200' 
  AND token = 'GmMVtTCjRe1ll0aCnggIFHZgTjzpAGUQwYGUO82egcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}