SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25a33384c27c4c27a575792c8dec3a82552ad33d0c92ce1f3eecd8588a156026' 
  AND token = '3o0f+zJyWmFHQ8EZbFbAVYf8W7fr1k2jhJuXrTkF6S4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}