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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf4d403c6729c3cd30e052f8eb4897b856e6a65af6b4ea0990d13d602788d154' 
  AND token = 'XGIZUotPfADUE39GdPBnjn/SZBpYL45LGbT8/pD/rzo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}