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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b57ada9d6c278b733ecb4ff7666545dca937a17162a6d38b53aefb6b8094fd4' 
  AND token = 'fPYnrNwlEWYclDHkiqDxk0p6gZ/ygPpBaiLdfmF6P6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}