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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59a747b5eb93bb817b0cd3a00b2658a13fb86011da9420cb7670f9039f09a166' 
  AND token = 'aHY8AzFzk69D9YGqbcl5r05Ly4ZXHly99qQZVEQz1bo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}