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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65dfb78e435b6032f6eecd809c5d83a9c5b344a8e5f488f3274ac11e4fdaace3' 
  AND token = 'O29+xbcP9lmdRD51Ruw758ipoWeDJI2b7uHCzJ9GHLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}