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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81e3e86baccf169d9ccb1b1d5d167cedb81bb6e9f2450f33781912fa6a428d65' 
  AND token = 'vTQ78Pb4yzX2aeJiYb/bDid20n0mUGcFEF0XItTotDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}