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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d5e010602912066ee491ba1a539058fe5ffd31b72b47589575ca2701929c414' 
  AND token = '3SqMQTpa5NCrowGza0dMXWOerre+0jTsuCKY6POe918=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}