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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25e9b202c7a3d64a4f275a3a4278c86b2e52d461a5ad78ddce0888b3f2699585' 
  AND token = 'KZDqDT+Mu2tKFS/TUQqdc3axKO3oef/hyAE+jX5QhHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}