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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9eacb61b451bcf5ed980624630b1a4462f0882527b6bc6c54db1375c4af6d7d9' 
  AND token = 'QCPzl6Xb74owKkvAALVBqXYtdLndfWnvh6TrBg0CBNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}