SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca9b35e7fe2cbf33cac9f8f4164c01538a6b90cedacf5008fb8534b128cadad2' 
  AND token = 'f3sa9qsLURw0Qa3IvQTjB9wlpkGvYZx4VjFE/ImcCGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}