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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f19f2d7cbb664554b996d4fb1337214cc72dbc04f842b7d527e1d7f2f77a3626' 
  AND token = 'pJbk21sC0LxwS7L+uRUPy9B4JZQBEPPraH5YYFmseY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}