SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26553ca5112dcaff640b0781b6aa4d301617cf58eb858c37f03d25ffe6780beb' 
  AND token = 'Gn59NqzZuiB8GeJl6kTC6TpVEEOJ0Y/5bnR9FIh6k5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}